Deltamethrin
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Class of drug
Description
Chemical name
- (s)-cyano-3-phenoxybenzyl-(1R,3R)-3-(2,2-dibromovinyl)-2,2-dimethyl-cyclopropanecarboxylate.
Physical properties
Storage requirements
Action
Contact:
- Anti parasitic blood feeding.
- Repellent.
- Knock-down/lethal effects.
Indications
- Prevents fly bites
. - Flea, tick or lice infestation .
Routes of administration
Topical:
- Pour-on.
- Spot-on.
- Impregnated collars.
Dosage
Basic dose
- 1% topical solution.
- 4% impregnation complex.
Normal
Topical absorption
- 1 - 2 weeks for effective levels to be reached
- Activity lasts < 7months.
Plasma concentrations
Distribution
- Passes readily into lipid film of dog's skin.
- Thereon spreads over surface of body.
Physiological, variations
Neonate
- Harmful to very young pups.
Pregnancy
- Can be used in pregnant bitches.
Lactation
- Can be used in lactating bitches.
Contra-indications
- Puppies < 7 weeks of age.
- Internal use
- Treatment of diseases associated with blood feeding insects
.
Interactions
with other drugs
- Triphenyl phosphate as an excipient for impregnated collars.
Effects of overdosage
- Oral ingestion of >300mg/kg is harmful but not fatal.
Other reported reactions
- Also toxic to aquatic animals.
- Minor skin irritation in all mammals.
Operators should wear protective clothing to avoid direct skin contact.
Manufacturers / brands
Single ingredient preparations
Publications
Refereed papers
- Reithinger R et al (2004) Are insecticide impregnated dog collars a feasible alternative to dog culling as a strategy for controlling canine visceral leishmaniasis in Brazil. Int J Parasitol 34 , 55-62.
Other sources of information
- Based on Small Animal Formulary. Tennant Bryn (1999) 3rd edn. Cheltenham: BSAVA. ISBN: 0 905214 44 7.
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