Meglumine antimonate
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Class of drug
Indications
- First choice treatment for canine leishmaniasis.
Animals may be clinically normal after treatment but still be carriers and follow up treatment with allopurinol 
may be beneficial.
Routes of administration
- Injectable: 300 mg/ml solution.
Dosage
Basic dose
- 100 mg/kg IM, slow IV SID until clinical remission achieved.
Pathological variations
Renal insufficiency
- Do not use in severe renal dysfunction.
Hepatic insufficiency
- Do not use if severe liver dysfunction.
Other reported reactions
- Intolerance is rare but wise to start with one-half dosage and increase gradually to effective dose.
Publications
Other sources of information
- Based on Small Animal Formulary. Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.
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